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Dr. D. Sprengers

Board member Foundation for Liver and Gastrointestinal Research

Hepatologist at Erasmus MC

Biography

From the bench to the hepatology clinic. As a clinician with a strong emphasis on lab research, it is my aim to translate research data to clinical implementation. The focus of my research is on immunopathology of liver cancer and chronic liver disease and because we have a unique collaboration between lab scientists and clinicians easy translation from the bench to the bedside can be achieved!
 

CLINICAL EXPERIENCE

  • Oktober 2013 - present: consultant Gastroenterology and Hepatology, Dept. of Gastroenterology and Hepatology, Erasmus MC, Rotterdam, The Netherlands. Special focus on hepatology.

  • January 2012 - September 2013: consultant Gastroenterology and Hepatology, Dept. of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands. Special focus on hepatology.

  • January 2005 - December 2011: Trainee Gastroenterology and Hepatology at Erasmus MC, Rotterdam, The Netherlands

  • 1994 - 2001: KUN Nijmegen; medicine: propaedeutics July 1995 certificate April 2001 (cum laude).
     

SCIENTIFIC EXPERIENCE

  • May 2016 - present: co-supervision of PhD's and postdocs with focus on immunopathology in patients with hepatocellular carcinoma (HCC). 

  • January 2009 - 2015: Erasmus MC Fellowship award: Title; The role of regulatory T cells and NKT cells in suppression of tumor surveillance in patients with hepatocellular carcinoma. Starts own lab and research group with focus on immunopathology in liver cancer; co-supervising a postdoc, technicians and PhD students.

  • January - December 2006: post-doc research at Harvard Medical School, Boston, USA. Supervised by Dr. M. Boes; title: the role of NKT cells in the intrahepatic immune response.

  • April 2001 - December 2004: PhD research at Dept of Gastroenterology and Hepatology at Erasmus MC supervised by prof Dr. H.L.A. Janssen. Title thesis: Immune response and immunomodulation in chronic hepatitis B virus infection. Date of defense 1/11/2006. 

  • August 1999 - April 2000: Research elective at The Division of Digestive Diseases of the University of North Carolina at Chapel Hill; USA, supervised by prof. R.B. Sartor and dr. L.A. Dieleman; title: the role of intestinal flora in inflammatory bowel disease.

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